Abstract Search

ea0040p4 | (1) | ESEBEC2016

Expression of osteopontin isoforms is related with thyroid cancer growth and invasion

Ferreira Luciana Bueno , Tavares Catarina , Pestana Ana , Leite Catarina , Eloy Catarina , Rios Elisabete , Celestino Ricardo , Batista Rui , Sobrinho-Simoes Manuel , Gimba Etel , Soares Paula

Osteopontin (OPN) is a matricellular protein highly expressed in cancer cells, which is able to modulate tumorigenesis and metastasis in several malignancies, including follicular cell-derived thyroid cancers (TC). OPN is one of the gene products aberrantly expressed in TC, but the contribution of each OPN isoform (OPNi), named as OPNa, OPNb and OPNc, is currently unknown. This study aims to analyze the expression profile of OPNi in TC tissue samples, correlate its expression ...

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ea0035p1149 | Thyroid Cancer | ECE2014

Prognostic significance of TERT promoter mutations in follicular cell-derived thyroid carcinomas

Melo Miguel , da Rocha Adriana Gaspar , Vinagre Joao , Batista Rui , Peixoto Joana , Celestino Ricardo , Salgado Catarina , Eloy Catarina , Lima Jorge , Amaro Teresina , Lobo Claudia , Moura Margarida , Cavaco Branca , Leite Valeriano , Cameselle-Teijeiro Jose Manuel , Carrilho Francisco , Carvalheiro Manuela , Maximo Valdemar , Sobrinho-Simoes Manuel , Soares Paula

Context: Telomerase promoter mutations (TERT) were recently described in follicular cell-derived thyroid carcinomas (FCDTC) and seem to be more prevalent in aggressive cancers.Objectives: We aimed to evaluate the frequency of TERT promoter mutations in thyroid lesions and to investigate the prognostic significance of such mutations in a large cohort of patients with differentiated thyroid carcinomas (DTC).<p class="abstext"...

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Endocrine Abstracts

Expression of osteopontin isoforms is related with thyroid cancer growth and invasion

Prognostic significance of TERT promoter mutations in follicular cell-derived thyroid carcinomas

BiosciAbstracts